Moderate Evidence Research Overview

LL-37 Research for Infections

An evidence-based overview of research examining LL-37 in the context of infections. This page synthesizes findings from peer-reviewed literature.

Research Summary

LL-37 has broad-spectrum antimicrobial activity against bacteria, viruses, and fungi. The cationic peptide disrupts microbial membranes and has additional immunomodulatory effects that enhance pathogen clearance. Research demonstrates activity against both gram-positive and gram-negative bacteria, including antibiotic-resistant strains. The peptide is part of the innate immune response to infection. Clinical development has been limited by challenges in peptide delivery and stability. Topical formulations and synthetic analogs are under investigation.

Referenced Studies

Click any PMID to view the full study on PubMed.

Other Peptides Studied for Infections

Important Disclaimer

This page summarizes research findings and does not constitute medical advice. LL-37 may have regulatory approval for some indications but should only be used under qualified medical supervision. Always consult a healthcare provider before making health decisions.