What is TB-500?

An introduction to TB-500, a fragment of thymosin beta-4 marketed for tissue repair.

Last updated: January 28, 2026

What is TB-500?

TB-500 is a synthetic fragment of thymosin beta-4 (Tβ4), a naturally occurring protein involved in cell migration and wound healing. It is not approved by any regulatory agency.

Key Facts

FactDetail
ApprovedNo
Parent CompoundThymosin beta-4
Evidence LevelLow
WADA StatusProhibited

TB-500 vs Thymosin Beta-4

AspectTB-500Thymosin Beta-4
StructureFragmentFull protein
Human TrialsNone (TB-500)Some Phase 2
ResearchLimitedMore extensive

What’s Claimed?

TB-500 is marketed for:

  • Muscle and tendon healing
  • Wound recovery
  • Flexibility improvement

The Evidence Problem

  • TB-500 specifically has no human clinical trials
  • Research on the parent compound (Tβ4) cannot be directly applied
  • The fragment may behave differently than the full protein

Important Warnings

  • Products are unregulated with unknown purity
  • Safety is not established
  • Banned in competitive sports
  • Gained attention from horse racing scandals

This guide is for educational purposes only. TB-500 is not approved for any medical use.

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Disclaimer: This educational guide does not constitute medical advice. The information presented is based on current research but should not be used for diagnosis, treatment, or prevention of any disease. Always consult a qualified healthcare provider before making health decisions.