What is Ipamorelin?
An introduction to ipamorelin, a selective growth hormone secretagogue that was never approved.
Last updated: January 19, 2026
What is Ipamorelin?
Ipamorelin is a synthetic peptide that stimulates the body to release growth hormone. It was developed to be more selective than earlier GH-releasing peptides.
Key Facts
| Fact | Detail |
|---|---|
| FDA Approved | No |
| Development Status | Discontinued |
| WADA Status | Prohibited |
How Does It Claim to Work?
Ipamorelin binds to ghrelin receptors and stimulates growth hormone release from the pituitary gland. Unlike older peptides, it has minimal effects on cortisol and prolactin.
Why Isn’t It Approved?
Pharmaceutical development was discontinued. While some human studies were done, the development program was not completed, and no application for approval was submitted.
Selectivity Advantage
| Effect | GHRP-6 | Ipamorelin |
|---|---|---|
| GH Release | Yes | Yes |
| Cortisol | Increases | Minimal |
| Prolactin | Increases | Minimal |
| Appetite | Strong | Less |
Important Warnings
- Not approved for any medical use
- Available only through unregulated sources
- Long-term safety unknown
- Banned in competitive sports
This guide is for educational purposes only. Ipamorelin is not approved by regulatory agencies.
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Disclaimer: This educational guide does not constitute medical advice. The information presented is based on current research but should not be used for diagnosis, treatment, or prevention of any disease. Always consult a qualified healthcare provider before making health decisions.